福岡女子大学
福岡女子大学　地域連携センター
地域連携センター 女性生涯学習研究部門 研究支援部門 地域交流部門
研究者データベース
研究者 主要研究業績
国際文理学部 食・健康学科
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濱田　俊
教授

濱田　俊

ハマダ　シュン

主要研究業績　-　2016年度以前

  • Kaneko R, Sato A, Hamada S, Yagi T, Ohsawa I, Ohtsuki M, Kobayashi E, Hirabayashi M, Murakami T. (2016) Transgenic rat model of childhood-onset dermatitis by overexpressing telomerase reverse transcriptase (TERT). Transgenic Res., doi:10.​1007/​s11248-016-9939-3
  • Hamaguchi-Hamada, K., Kurumata-Shigeto, M., Minobe, S., Fukuoka, N., Sato, M., Matsufuji, M., Koizumi, O., Hamada, S.(2016) Thrombospondin Type-1 Repeat Domain-containing Proteins are Strongly Expressed in the Head Region of Hydra. PLoS ONE, 11(4), e0151823, doi:10.1371/journal.pone.0151823, 2016 PLoS ONE, 11(4), e0151823, doi:10.1371/journal.pone.0151823
  • Koizumi O., Hamada S., Minobe S., Hamaguchi-Hamada K., Kurumata-Shigeto M., Nakamura M., Namikawa H. (2015) The nerve ring in cnidarians: its presence and structure in hydrozoan medusae. Zoology 118(2), 79-88
  • Hamada, S., Hirashima, H., Imaeda, M., Okamoto, M., Hamaguchi-Hamada, K., Kurumata-Shigeto, M. (2013) Thiamine deficiency induces massive cell death in the olfactory bulbs of mice. J. Neuropathol. Exp. Neurol. 72(12), 1193-1202
  • Hasegawa S., Hirabayashi T., Kondo T., Inoue K., Esumi S., Okayama A., Hamada S., Yagi T. (2012) Constitutively expressed protocadherin-a regulates the coalescence and elimination of homotypic olfactory axons through its cytoplasmic reion. Front. Mol. Neurosci.5:97
  • Ohsawa S., Hamada S., Kuida K., Yoshida H., Igaki T., Miura M. (2010) Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity. Proc. Natl. Acad. Sci. USA 107(30), 13366-71
  • Ohsawa S., Hamada S., Asou H., Kuida K., Uchiyama Y., Yoshida H., Miura M. (2009) Caspase-9 activation revealed by Semaphorin 7A cleavage is independent of apoptosis in the aged olfactory bulb. J. Neurosci. 29(36), 11385-11392
  • Hattori K., Fukuzako H., Hashiguchi T., Hamada S., Murata Y., Isosaka T., Yuasa S., Yagi T. (2009) Decreased expression of Fyn protein and disbalanced alternative splicing patterns in platelets from patients with schizophrenia. Psychiatry Res. 168(2), 119-128
  • Hamaguchi-Hamada K., Fujisawa Y., Koizumi O., Muneoka Y., Okado N., Hamada S. (2009) Immunohistochemical evidence for the existence of novel mammalian neuropeptides related to hydra GLW-amide neuropeptide family. Cell Tissue Res. 337(1), 15-25
  • Katori S., Hamada S. (co-first author), Noguchi Y., Fukuda E., Yamamoto T.,　Yamamoto H., Hasegawa S., Yagi T.(2009) Protocadherin-a family is required for serotonergic projections of appropriately innervate target brain areas. J. Neurosci. 29(29), 9137-9147
  • Fukuda E., Hamada S., Hasegawa S., Katori S., Sanbo M., Miyakawa T., Yamamoto T., Yamamoto H., Hirabayashi T., Yagi T. (2008) Down-regulation of protocadherin-a A isoforms in mice changes contextual fear conditioning and spatial working memory. Eur. J. Neurosci. 28(7), 1362-1376, 2008. Eur. J. Neurosci. 28(7), 1362-1376
  • Hasegawa S., Hamada, S.(co-first author), Kumode, Y., Katori, S., Fukuda, E., Uchiyama, Y., Hirabayashi, T., Mombaerts, P., Yagi, T.(2008) The protocadherin-a family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse. Mol. Cell Neurosci. 38, 66-79
  • Ohsawa S., Hamada S., Yoshida H., Miura M. (2008) Caspase-mediated changes in histone H1 in early apoptosis: prolonged caspase activation in developing olfactory sensory neurons. Cell Death & Diff. 15(9), 1429-1439
  • 濱田　俊　(2007) 人体の構造と機能および疾病の成り立ち：疾病の成因・病態・診断・治療/執筆担当：９－B,C章 医歯薬出版
  • 濱田俊　八木健(2006) プロトカドヘリンとその機能/Protocadherins; classification, structures and functions 生化学　78（7）662-671
  • Osada T., Tamamaki N., Song S.Y., Kakazu N., Yamazaki Y., Makino H., Sasaki A., Hirayama T., Hamada S., Nave K.A., Yanagimachi R., Yagi T. (2005) Developmental pluripotency of the nuclei of neurons in the cerebral cortex of juvenile mice. J. Neurosci. 25(37), 8368-8374
  • Makino H., Yamazaki Y., Hirabayashi T., Kaneko R., Hamada S., Osada T., Kawamura Y., Yanagimachi R., Yagi T. (2005) Mouse embryos and chimera cloned from neural cells in the postnatal cerebral cortex. Cloning Stem Cells 7(1), 45-61
  • 村田陽二、濱田俊、八木健(2005) 神経系における多様化膜分子群：CNR／プロトカドヘリンファミリー 神経研究の進歩　49(1)　115-127
  • Esumi S., Kakazu N., Taguchi Y., Hirayama T., Sasaki A., Hirabayashi T., Koide T., Kitsukawa T., Hamada S., Yagi T. (2005) Monoallelic yet combinatorial expression of variable exons of the CNR/Protocadherin-α gene cluster in single neurons. Nature Genetics 37(2), 171-176, 2005
  • Ohsawa S., Hamada S., Kakinuma Y., Yagi T., Miura M.(2005) A novel function of neuronal PAS domain protein 1 (NPAS1) in erythropoietin expression in neuronal cells. J. Neurosci. Res. 79(4), 451-458
  • Morishita H., Murata Y., Esumi S., Hamada S., Yagi T.(2004) CNR/Pcdhα family in subplate neurons, and developing cortical connectivity. Neuroreport 15(17), 2595-2599
  • Morishita H., Kawaguchi M., Murata Y., Seiwa C., Hamada S., Asou H., Yagi T.(2004) Myelination triggers down-regulation of axonal CNR/Protocadherin family expression. Eur. J. Neurosci. 20(11), 2843-2847
  • Murata, Y., Hamada, S., Morishita, H., Mutoh, T., Yagi, T.(2004) Interaction with Protocadherin-gamma regulates the cell-surface expression of Protocadherin-alpha. J. Biol. Chem. 279, 49508-49516
  • Hamaguchi-Hamada K., Hamada S., Yagi T. (2004) Exposure to hexanal odor induces extraordinary Fos expression in the medial preoptic area and amygdala of Fyn tyrosine kinase-deficient mice. Mol. Brain Res. 130 187-190 Mol. Brain Res. 130 187-190
  • Hamaguchi-Hamada K., Sanbo C., Hamada S., Yagi T. (2004) Exposure to hexanal odor influences maternal behavior and induces neonatal death in Fyn tyrosine kinase-deficient mice. Neurosci. Res. 48(3) 259-67
  • Sugino H., Yanase H., Hamada S., Kurokawa K., Asakawa S., Shimizu N., Yagi T. (2004) Distinct genomic sequence of the CNR/Pcdhalpha genes in chicken. Biochem. Biophys. Res. Commun. 316(2) 437-45
  • MutohT., Hamada S., Senzaki K., Murata Y., Yagi T. (2004) Cadherin-related neuronal receptor 1 (CNR1) has cell adhesion activity with β1 integrin mediated through the RGD site of CNR1. Exp. Cell Res. 294(2) 494-508
  • 濱田俊　八木健(2003) 神経系における多様化膜分子群：遺伝子クラスターを形成するCNR／プロトカドヘリンファミリー 比較生理生化学　20(1) 3-8 2003
  • Yagi T., Tada M., Tanaka Y., Senzaki K., Hirayama T., Hamada S., Sugino H. Diversity of the cadherin-related neuronal receptor family in the nervous system. (2002) Diversity of the cadherin-related neuronal receptor family in the nervous system Int. Congress Series 1246 127-136
  • Yamazaki Y., Makino H., Hamaguchi-Hamada K., Hamada S., Sugino H., Kawase E., Miyata T., Ogawa M., Yanagimachi R., Yagi T. (2001) Assessment of the developmental totipotency of neural cells in the cerebral cortex of mouse embryo by nuclear transfer. Proc. Natl. Acad. Sci. USA 98(24) 14022-6
  • Hamada S., Yagi T. (2001) The cadherin-related neuronal receptor (CNR) family: a novel diversified cadherin family at the synapse. Neurosci. Res. 41(3) 207-215
  • Takei Y., Hamada S., Senzaki K., Mutoh T., Sugino H., Yagi T. (2001) Two Novel CNRs from the CNR gene cluster have molecular features distinct from those of CNR1-8. Genomics 72 321-330
  • 濱田俊　八木健(2000) シナプス形成とカドヘリンスーパーファミリー　- 選択的シナプス結合形成の分子基盤か？ - 脳２１ 3(4) 419-426
  • Shutoh F., Hamada S., Shibata M., Narita M., Shiga T., Azmitia E. C., Okado N.(2000) Long term depletion of serotonin leads to selective changes in glutamate receptor subunits. Neurosci. Res. 38(4) 365-371
  • Maxishima M., Shiga T., Shutoh F., Hamada S., Maeshima T., Okado N.(2000) Serotonin 2A receptor-like immunoreactivity is detected in astrocytes but not in oligodendrocytes of rat spinal cord Brain Res. 889 270-273
  • 濱田香世子、濱田俊(2000) ジーンターゲッティングの最新技術（執筆担当：３-１章　「解剖学的解析法」、132-142）　羊土社 執筆担当：３-１章　「解剖学的解析法」、132-142 羊土社
  • Sugino H., Hamada S. (co-first author), Yasuda R., Tuji A., Matsuda Y., Fujita M., Yagi T. (2000) Genomic organization of the family of CNR cadherin genes in mice and human. Genomics 63(1) 75-87
  • Maeshima T., Shutoh F., Hamada S. (corresponding author), Senzaki K., Hamaguchi-Hamada K., Ito R., Okado N. (1998) Serotonin2A receptor-like immunoreactivity in rat cerebellar Purkinje cells. Neurosci. Lett. 252(1) 72-74
  • Maeshima T., Ito R., Hamada S., Senzaki K., Hamaguchi-Hamada K., Shutoh F., Okado N. (1998) The cellular localization of 5-HT2A receptors in the spinal cord and spinal ganglia of the adult rat. Brain Res. 797(1) 118-124
  • Hamada S., Senzaki K., Hamaguchi-Hamada K., Tabuchi K., Yamamoto T., Yoshikawa S., Okano H., Okado N. (1998) Localization of 5-HT2A receptor in rat cerebral cortex and olfactory system revealed by immunohistochemistry using two antibodies raised in rabbit and chicken. Mol. Brain Res. 54(2) 199-211
  • Kohmura N., Senzaki K., Hamada S., Kai N., Yasuda R., Watanabe M., Ishii H., Yasuda M., Mishina M., Yagi T. (1998) Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex. Neuron 20 1137-1151
  • Chen L., Hamaguchi K., Hamada S., Okado N. (1997) Regional differences of serotonin-mediated synaptic plasticity in the chicken spinal cord with development and aging. J. Neural Transplant. Plast. 6. 41-48. 1997 J. Neural Transplant. Plast. 6 41-48
  • Hamada S., Ogawa M., Okado N. (1995) Immunohistochemical examination of intraspinal serotonin neurons and fibers in the chicken lumbar spinal cord and coexistence with leu-enkephalin. Cell Tissue Res. 282. 387-397. 1995 Cell Tissue Res. 282 387-397
  • Niitsu Y., Hamada S.(co-first author), Hamaguchi K., Mikuni M., Okado N. (1995) Regulation of synapse density by 5-HT2A receptor agonist and antagonist in the spinal cord of chicken embryo. Neurosci. Lett. 195. 159-162
  • 濱田俊、浜口香世子、陳玲、岡戸信男 　(1994) セロトニンの非伝達物質機能：シナップスの形成と維持に果たす役割。　脳と精神の医学　5(1). 87-92. 1994/Non-transmitter function of serotonin: Role for formation and maintenance of synapses
  • Chen L., Hamaguchi K., Ogawa, M., Hamada S., Okado N. (1994) PCPA reduces both monoaminergic afferents and nonmonoaminergic synapses in the cerebral cortex. Neurosci Res. 19 111-115
  • 岡戸信男、濱田俊　(1993) セロトニンニューロンと発生・分化/Serotoninergic neurons for ontogeny and differentiation 実験医学　11(10) 126-132 羊土社
  • Okado N., Cheng L., Tanatsugu Y., Hamada S., Hamaguchi K.(1993) Synaptic loss following removal serotonergic fibers in newly hatched and adult chickens. J Neurobiol. 24 687-698
  • Okado N., Matsukawa M., Noritake S., Ozaki S., Hamada S., Arita M., Kudo N.(1991) Species differences in the distribution and coexistence ratio of serotonin and substance P in the monkey, cat, rat and chick spinal cord. Neurosci. Lett. 132(2) 155-158

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